• Tamping: Fine-Tuning Capsule Filling

    If you’re thinking about encapsulating high-volume, well- formulated products, a tamper-style encapsulator is your best bet (dosator-style encapsulators work with sticky products, while hand-filling-style machines handle coarse products and small volumes well) Tamper-style encapsulators use pins to push through a pile of powder, forcing an ambiguous amount into a dosing bore. This is repeated several times prior to transfer into the capsule body. The capsule’s contents is called a “slug”. An ... read more
  • Adverse Event Reporting: “Over the Counter” Doesn’t Mean “Off the Hook”

    As part of its mission to protect the public health, the FDA monitors the safety of drug products marketed in the United States. This is accomplished through laws enacted by Congress as well as regulations established by the agency that require the pharmaceutical industry to document and, as applicable, report adverse events experienced by both patients and consumers when using their products. For OTC drugs that are not marketed under an NDA or ANDA, documentation of adverse events at one time ... read more
  • Improving Coating Quality: New Technologies Promise Improvements

    Although coating has been a standard part of pharmaceutical tablet and pellet production for decades, some problem areas still persist — quality, productivity, and flexibility. Aspects of these problems are sometimes accepted or overlooked, due to presumed lack of solutions. But improvements are possible, and some technological breakthroughs are particularly promising. read more
  • Choosing the Best Imprinting Machine for your Pharmaceutical Product Identity

    Oral Solid Dosage Formulations (OSDF) bring progress with medicines that improve health and quality of life. The process to progress however, goes unseen by customers when they do not recognize your pharmaceutical product as the artwork it is. Every OSDF must be imprinted with an identifiable code by regulation, but is being identified enough after it all? read more