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This Month’s Focus: Capsule Filling

Selecting the final SODF: A comparison of capsules and tablets

Many variables come into play when selecting the final dosage form of a drug product. Among them are the formulation, manufacturing process, scalability, validation requirements, quality control, cost, and patient perception and preference.

Abuse-deterrent formulation technologies: Opportunities and limitations

Too many Americans are misusing or abusing prescription opioids. This article summarizes recent FDA initiatives in this area and assesses the technologies manufacturers have adopted to curb abuse.

Back Page: Troubleshooting common capsule defects

Capsules are fairly easy to fill, but sometimes things go wrong. Here are some tips on how to stop defects.

General Features

Scaling up wet high-shear mixer granulation

High-shear granulation is notoriously difficult to design and scale up, mainly because of the many operating parameters and competing mechanisms occurring in the granulator.

Spotlight on Nutraceuticals: Rice-based excipient solves PureNSM’s sticky situation

Replacing conventional excipients with riced-based alternatives enables company to handle difficult-to-tablet products, grow its clean-label business

Eye on Excipients: Effect of HPC molecular weight on granules and tablets prepared by two wet granulation methods

The authors studied six different grades of HPC to determine how they performed in high-shear and fluid-bed granulation.

March Content

Formulating fixed-dose combinations

India: A new sourcing hub for excipients?

Trends in the solid oral drug delivery market

Issue Focuses

January: Capsule Filling

March: Outsourcing

April: Coating

May: Packaging

June: Solid Dosage Sourcebook

July: Excipients & Formulation

September: Tabletting

October: Quality, Validation & Regulatory Compliance

November: Annual Buyer’s Guide

Contact the editor:
Nate Todd
1155 Northland Drive
St. Paul, MN 55120
Fax 651-287-5650

Thank You!

T&C relies on professionals like you to keep our readers informed about the latest technology, methods, and equipment. Thank you for considering T&C for placement of your article.

Special Sections
Capsule Filling
Granulation & Drying
Outsourcing: Formulation, Manufacturing, Packaging, Research & Lab Services
1. Counters/Bottle Fillers
2. Dedusters
1. Test & Inspection Equipment
2. Multi-layer Tabletting
1. Particle Size: Reduction,     Separation, & Analysis
2. Powder Transfer &     Containment
Solid Dosage Sourcebook
Excipients & Formulation
1. Tooling
2. Mixers & Blenders
Liquid Capsule Filling
Quality, Validation, & Regulatory Compliance
1. Blister Packaging
2. Tablet & Capsule      Identification
Annual Buyer’s Guide
*Issue includes “Spotlight on Nutraceuticals” insert.

Buyers Guide
Tables and Capsules Source Book