This Month’s Focus: Capsule Filling
Selecting the final SODF: A comparison of capsules and tablets
Many variables come into play when selecting the final dosage form of a drug product. Among them are the formulation, manufacturing process, scalability, validation requirements, quality control, cost, and patient perception and preference.
Abuse-deterrent formulation technologies: Opportunities and limitations
Too many Americans are misusing or abusing prescription opioids. This article summarizes recent FDA initiatives in this area and assesses the technologies manufacturers have adopted to curb abuse.
Back Page: Troubleshooting common capsule defects
Capsules are fairly easy to fill, but sometimes things go wrong. Here are some tips on how to stop defects.
Scaling up wet high-shear mixer granulation
High-shear granulation is notoriously difficult to design and scale up, mainly because of the many operating parameters and competing mechanisms occurring in the granulator.
Spotlight on Nutraceuticals: Rice-based excipient solves PureNSM’s sticky situation
Replacing conventional excipients with riced-based alternatives enables company to handle difficult-to-tablet products, grow its clean-label business
Eye on Excipients: Effect of HPC molecular weight on granules and tablets prepared by two wet granulation methods
The authors studied six different grades of HPC to determine how they performed in high-shear and fluid-bed granulation.
Formulating fixed-dose combinations
India: A new sourcing hub for excipients?
Trends in the solid oral drug delivery market
January: Capsule Filling
June: Solid Dosage Sourcebook
July: Excipients & Formulation
October: Quality, Validation & Regulatory Compliance
November: Annual Buyer’s Guide
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2. Multi-layer Tabletting
2. Powder Transfer & Containment
2. Mixers & Blenders
2. Tablet & Capsule Identification