Under the US Drug Supply Chain Security Act (DSCSA), by November 27, 2023, all drug product manufacturers, repackagers, distributors, and dispensers must exchange transaction information and statements in an interoperable electronic manner at the package level (track and trace). This article summarizes a report submitted to the FDA by the MediLedger Pilot Project demonstrating that a system using blockchain technology can achieve compliance with the DSCSA track and trace requirements.

Packaging is critical in cannabis production because it delivers and presents the product to the consumer. This article discusses how producers and distributors can best position their CBD products to meet potential future regulations and increase the bottom line.

In this article, industry leaders discuss the importance of sustainability in pharmaceutical packaging, what they’re doing to promote and support sustainable efforts within their companies and organization, and the impact of environmental concerns on the future of pharmaceutical packaging.

Solid dosage manufacturers and contract packagers typically consider automating manual operations when significant, immediate problems are causing line downtime or when they can no longer tolerate an ongoing series of problems. Some companies plan to automate upon reaching a goal or growth milestone, but more often, companies automate when they realize it’s the only way, or the most effective way, to be profitable.

The 47th annual Controlled Release Society (CRS) meeting and exposition is slated to take place June 27-July 1 at the Paris Hotel, Las Vegas, NV. Organizers are continuing to monitor updates regarding the COVID-19 pandemic and following the latest advice from the CDC, WHO, and state and local governments. Should public health considerations or federal, state, and local restrictions make it unsafe and impractical to run the conference, the event will be canceled. For the latest updates, visit 2020.controlledreleasesociety.org.

When pneumatically transferring highly potent active pharmaceutical ingredients, containment is critical. This article discusses containment standards for highly potent materials, describes how modern vacuum conveying systems can help meet those standards, and provides two real-world examples of custom-designed vacuum conveying systems for high-potency applications.

Manufacturers favor continuous direct compression of tablet formulations because it is economical and efficient, but the process presents a variety of manufacturing challenges related to content uniformity, compactibility, and flow. This edition of “Eye on Excipients” explores a method for incorporating a co-processed excipient into a tablet formulation to facilitate direct compression tableting and create more robust tablets.