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The only technical publication dedicated to readers who formulate, manufacture, or package solid dosage forms.

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T&C Digital Edition
Tables and Capsules Solid Dose Digest E-Newsletter
Tables and Capsules Source Book
TC Magazine

Cover Photo Courtesy of
Syntegon

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This Month’s Focus: Tableting

Minitablets and microtip tooling

This article discusses minitablet manufacturing and microtip tooling, including how formulation characteristics and tablet design affect minitablet production; critical tablet press settings and options; and how to determine the proper tablet press overload settings.

The science behind sticking and how to resolve it

Sticking is often described as the Achilles’ heel of tablet production. It is one of the most common tablet tooling problems and can have a profound effect on production, leading to reduced output and increased costs. This article explains why sticking occurs and proposes several solutions.

Back Page: Counterfeiters: Turn in or turn away?

Counterfeiting is a huge problem in the pharmaceutical industry, where a fake product can not only cause dissatisfaction related to performance but may also cause injury and, in extreme cases, death. When we purchase a pharmaceutical product, we have a high expectation that it is safe, but with counterfeits, this isn’t always the case. Our sense of security is weakened each time a new counterfeit drug product is discovered.

General Features

Water activity and moisture: The complexity and interrelationships explained

Water activity and moisture content both represent a measure of water in a material. While the terms are often confused with each other, they are two very different parameters, and understanding the difference can be important for the development of robust pharmaceutical formulations. This article evaluates the two parameters and discusses their relevance for the stability of solid dosage formulations.

PharmSci 360: a preview

PharmSci 360, the annual meeting of the American Association of Pharmaceutical Scientists (AAPS), has gone completely virtual in light of the ongoing COVID-19 pandemic. Virtual attendees can access the educational sessions, exhibition floor, and other content from October 26-November 5, and all posters, symposia, and career development recordings will be available to registered participants until December 31.

Gelatin supply disruptions threaten US pharmaceutical manufacturers

This article describes how COVID-19 and other factors have led to increased risk of interruptions to the US pharmaceutical supply chain and discusses how sourcing ingredients more locally can benefit manufacturers and US consumers.

Using near-infrared spectroscopy and chemometric modeling to simultaneously determine ibuprofen and caffeine concentration in softgels

This article summarizes a method for rapid and accurate determination of API concentration in the fill of soft gelatin capsules with little or no sample preparation. Applying chemometric models to near-infrared spectrum data allows scientists to predict the API content in samples from the manufacturing process and the final product.

Eye on Excipients: Using a co-processed excipient in direct-compression orally disintegrating tablets

This edition of Eye on Excipients describes a study conducted to evaluate the suitability of a novel co-processed excipient for use in orally disintegrating tablets and direct compression tableting. The characteristics evaluated included disintegrability, compactability, stability, and content uniformity.

October Content

COVID-19’s impact on FDA inspections and manufacturer risk

Excipient quality: Beyond the pharmacopeia monograph

Using Quality by Design to improve drug product development outcomes

Issue Focuses

January: Capsule Filling

March: Outsourcing

April: Coating

May: Packaging

June: Solid Dosage Sourcebook

July: Excipients & Formulation

September: Tableting

October: Quality, Validation & Regulatory Compliance

November: Annual Buyer’s Guide

Tablets & Capsules Technical Article Guidelines

Tablets & Capsules is the world’s only publication dedicated to solid dosage forms. Our readers are the people responsible for the formulation, production, and packaging of pharmaceutical and nutraceutical tablets and capsules in North America. Each issue reaches about 10,000 readers whose job functions include R&D, QC, engineering, and operations. All are technical decision-makers who need practical information.

T&C’s technical articles are written by technical professionals for technical professionals. But they are a collaborative effort: You provide the content and expertise, and T&C’s editors tailor your article to T&C’s audience.

For sample topics and details on how to submit an article and share your expertise, download the full technical article guidelines below or contact the editor.

Contact the editor:
Nate Todd
1155 Northland Drive
St. Paul, MN 55120
651-287-5625
ntodd@cscpub.com
2020
Focus
Special Sections
January*
Capsule Filling
Granulation & Drying
March
Outsourcing: Formulation, Manufacturing, Packaging, Research & Lab Services
1. Counters & Bottle Fillers
2. Dedusters
April*
Coating
1. Test & Inspection Equipment
2. Multi-layer Tableting
May
Packaging
1. Particle Size: Reduction,     Separation, & Analysis
2. Powder Transfer &     Containment
June
Solid Dosage Sourcebook
July*
Excipients & Formulation
1. Tooling
2. Mixers & Blenders
September
Tableting
Liquid Capsule Filling
October*
Quality, Validation, & Regulatory Compliance
1. Blister Packaging
2. Tablet & Capsule      Identification
November
Annual Buyer’s Guide
*Issue includes “Spotlight on Nutraceuticals” insert.

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Buyers Guide
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