This Month’s Focus: Excipients & Formulation
Developing oral controlled-release drug products
This article describes the various types of oral controlled-release (OCR) dosage forms and discusses the factors to consider when developing an OCR drug product.
Using next-generation HPMC polymers as an alternative to gelatin for hard capsules
As formulators increasingly prioritize speed to market, innovations have led to next-generation HPMC capsules that provide consistent dissolution performance, prevent crosslinking, and improve compatibility with moisture-sensitive APIs. This article describes how these differentiators provide drug developers seeking immediate-release dosage forms with an alternative to gelatin capsules.
Taste masking orally disintegrating tablet formulations
Orally disintegrating tablets (ODTs) are rising in popularity because of their ease of administration and improved patient compliance, creating the need for excipients that enable both taste masking and rapid disintegration. This article describes a method for taste masking ODT formulations by coating the active pharmaceutical ingredient (API) with an aqueous ethylcellulose polymer dispersion combined with different plasticizers.
Excipients and continuous manufacturing
This article discusses the role of excipients in the pharmaceutical industry’s adoption of continuous manufacturing and describes ways in which stakeholders can facilitate the transition to continuous processes.
How understanding material deformation characteristics can improve tableting process scale-up
This article describes how material deformation characteristics can influence tableting performance and explains how understanding your excipients’ deformation characteristics can help you plan for successful process scale-up.
Back Page: Current discussions in Europe regarding titanium dioxide safety
This article discusses a planned ban on food products containing titanium dioxide in France and its potential implications for the pharmaceutical industry.
Blending and tablet compression: Air percolation
This article is the first in a two-part series discussing how blending practices can influence tablet compression. The second part will appear in Tablets & Capsules’ September 2019 issue.
Spotlight on Nutraceuticals: Dust collection systems for dietary supplement manufacturing processes
This article discusses the significance of dust collectors in the nutraceutical industry and describes a procedure for verifying a dust collection system’s efficiency.
SupplySide West preview
SupplySide West—a trade show that provides educational and networking resources for professionals in the dietary supplement, food, beverage, personal care and sports nutrition industries—takes place October 15-19 in Mandalay Bay Hotel, Las Vegas, NV. Organizers anticipate more than 1,300 exhibitors and 17,000 attendees from the health and nutrition industry.
Spotlight on Nutraceuticals: Make it or break it: How tablet design and tooling choice can help or hinder nutraceutical manufacture
Tableting can be a challenge for nutraceutical manufacturers, especially if the tooling used is not appropriately designed for the formulation. This article discusses tablet-design and tool-steel considerations that can lengthen tooling service life and boost production.
Instrumentation and data acquisition on R&D tablet presses
Flashing during tablet compression
Developing combination products with liquid-filled hard capsules
January: Capsule Filling
June: Solid Dosage Sourcebook
July: Excipients & Formulation
October: Quality, Validation & Regulatory Compliance
November: Annual Buyer’s Guide
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2. Multi-layer Tableting
2. Powder Transfer & Containment
2. Mixers & Blenders
2. Tablet & Capsule Identification