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Q: Can we use a pneumatic conveyor to transfer oral solid dosage formulations without creating segregation, particle degradation, or containment issues?
A common misconception in the pharmaceutical industry is that pneumatic conveying leads to segregation and other issues, but this idea is based on outdated technology. While segregation is a major issue when transferring oral solid dosage formulations (OSDFs) between manufacturing operations, vacuum pneumatic conveying can resolve this issue while preventing particle degradation and safely containing the formulation.
Tips for a successful encapsulation process
This article discusses the primary factors that influence capsule filler performance and provides tips for optimizing your encapsulation process.
In Tablets & Capsules magazine
Reduce powder processing risks when outsourcing manufacturing
When outsourcing manufacturing for an oral solid dosage product, brand owners generally minimize risk by ensuring that the contract manufacturing organization's (CMO's) unit operations have the desired capability and have been tested with the target formulation and that the area has sufficient containment and environmental controls. They also typically confirm that the CMO's site leadership team has a demonstrated commitment to quality, analytics, and regulatory compliance. An area of risk that is often overlooked, however, is powder transfer between unit operations.
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