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Tablets & Capsules SDD

imageIn this issue of T&C Solid Dose Digest:

 
 
 
 
 
 
 
elizabeth

Wilson
 
Ask an Expert
 
Vegetarian softgels
 
Q: How do vegetarian softgels differ from animal-based softgels, and what are the types of vegetarian softgels available?
 
 
Pharmaceutical manufacturers' interest in vegetarian softgels has increased, driven by consumers' overall awareness of and demand for plant-based products, for clean-label products with recognizable ingredients, and for more socially responsible products with reduced carbon footprints. Consumers often associate nonanimal products with clean labeling.
 
 
 
CapsCanada

USP
 
More Questions and Answers
 
Turret wear
 
Q: How can we minimize wear on our tablet press turret and repair existing wear and damage?
 
 
imageOn a rotary tablet press, the turret is the circular, rotating component that holds and aligns the tooling—punches and dies—during operation. The turret is the heart of a rotary tablet press and is critical to manufacturing high-quality tablets. As the turret rotates, the punches move up and down at high speed, held in alignment by the punch guides, which are holes bored through the turret's upper and lower punch sections.
 
 
 
Gelita

Natoli
 
In Tablets & Capsules magazine
 
Improving CoQ10 ODT formulation for increased patient compliance
 
Jiantao Zhang, Yidan Lan, Ashish Joshi, and Nigel Langley, BASF
 
This article discusses how an orally disintegrating tablet formulation for CoQ10 was developed to improve mouthfeel compared to a commercial analog.
 
Coenzyme Q10 (CoQ10) is an effective antioxidant that plays a fundamental role in cellular bioenergetics, offers cardiac health benefits, and prevents cell damage from free radicals. However, many commercial CoQ10 dietary supplements are capsule products that can be hard to swallow for geriatric patients [1]. Orally disintegrating tablets (ODTs) offer nutraceutical manufacturers a solution for patients that experience dysphagia and other swallowing difficulties when taking solid oral dosage products. ODTs dissolve rapidly in contact with saliva, eliminating the need to chew or swallow the tablet, which can improve compliance among the geriatric population. The drawback of poorly formulated ODTs is that they often have a sandy/gritty mouthfeel and lack the organoleptic properties (taste and aftertaste) that patients desire. To fully meet consumers' needs and improve patient compliance, a CoQ10 ODT should disintegrate quickly without compromising taste and mouthfeel.
 
This article describes a study that compared a commercial CoQ10 ODT product with a formulation designed to exhibit improved taste and disintegration characteristics.
 
To learn more about this topic, you can read the article "Spotlight on Nutraceuticals: Improving CoQ10 ODT formulation for increased patient compliance.." You can also find articles under "Excipients," "Formulation," and "Orally disintegrating tablets" in Tablets & Capsules' Article Archive.
 
 
MFG Tray Co

Ackley
 
Industry news
 
 
 
 
 
 
 
 
 
 
 
Camfil

Camfil
 
Supplier news
 
 
 
 
To find more information about suppliers at the Tablets & Capsules website, click here.
 
 
Vac-U-Max

Vac-U-Max
 
Events and continuing education
 
Please check event websites for the most up-to-date information, because conferences and seminars may be canceled or postponed due to the developing COVID-19 pandemic.
 
 
 
 
 
 
 
 
 
To find more events and continuing education opportunities at the Tablets & Capsules website, click here.
 

TC Article Archive
April 6, 2020
 
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Supplier Resources
click below for more info
 
USP
 
Vac-U-Max
 
Wilson
 
Ackley
 
Camfil
 
Camfil
 
Camfil
 
CapsCanada
 
Gelita
 
MFG Tray
 
elizabeth
 
Natoli
 
Supplier Directory
 
Anti-Counterfeiting
Ackley Machine

Capsule Filling Equipment
Natoli Engineering
Vac-U-Max

Contract Formulation/
Manufacturing & Packaging

CapsCanada

Conveying/Mechanical
VAC-U-MAX

Dedusters
Elizabeth Scheu & Kniss
Natoli Engineering

Dust Collectors
Camfil APC
Elizabeth Scheu & Kniss

Empty Capsules
CapsCanada
Embocaps by Suheung

Excipients
CapsCanada
USP

Feeders
Ackley Machine
Elizabeth Scheu & Kniss

Inspection Equipment
Ackley Machine
Elizabeth Scheu & Kniss
Natoli Engineering

Metal Detectors/X-Ray Detectors
Elizabeth Scheu & Kniss
Natoli Engineering

Packaging Equipment
Ackley Machine
Elizabeth Scheu & Kniss
VAC-U-MAX

Pneumatic Conveying
VAC-U-MAX

Services
Ackley Machine
CapsCanada
Elizabeth Scheu & Kniss
Natoli Engineering

Softgels
Ackley Machine
MFG Tray Company

Storage/Bulk Handling
MFG Tray Company
VAC-U-MAX

Tablet & Capsule Printers
Ackley Machine
CapsCanada

Tablet Presses
Elizabeth Scheu & Kniss
KORSCH
Natoli Engineering

Testing
Natoli Engineering

Tooling
Elizabeth Scheu & Kniss
KORSCH
Natoli Engineering
Wilson Tool

Vacuum Cleaners
VAC-U-MAX

Validation
USP

Weighing Equipment
VAC-U-MAX
 
T&C Solid Dosage Sourcebook
 
sourcebook

Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Kyle Myers
T&C Solid Dose Digest
Circulation
kmyers@cscpub.com
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
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