If this newsletter is not displaying correctly, view an alternate version here.
To ensure delivery of our emails to your inbox, please add tcnews@cscpublishinginc.com to your address book.
 
Tablets & Capsules SDD

imageIn this issue of T&C Solid Dose Digest:

 
 
 
 
 
 
 
MFG Tray Co

Ackley
 
Ask an Expert
 
Dissolution testing
 
Q: How can I reduce the costs and environmental impact of dissolution testing?
 
 
imageOne way that you can save money and reduce your carbon footprint is by decreasing the electricity consumption of your dissolution testing. With USP Apparatus 1 and 2 dissolution testers, a conventional water-bath system heats the vessels and the dissolution medium they contain. Bathless instruments can perform as well as or better than conventional water-bath instruments while eliminating the water bath and consuming less electricity. The electricity savings in a dissolution lab could be substantial.
 
 
 
Camfil

Vac-U-Max
 
More Questions and Answers
 
Filter media
 
Q: How do filter media, air-to-media ratio, and airflow affect dust collection in our tableting operation?
 
A: David Steil, Camfil Air Pollution Control, says:
 
imageTo keep your dust collector operating efficiently over its lifetime, you must select the right filters and filter media, which requires that you understand how the system's air-to-media ratio affects its operation. A dust collector's air-to-media ratio, sometimes referred to as the air-to-cloth ratio, is the volume of air flowing through each square foot of filter media per minute.
 
 
 
Wilson

CapsCanada
 
In Tablets & Capsules magazine
 
Formulation effects on tablet surface properties and film coating adhesion
 
 
This article is based on the master thesis "Investigation of the influence of functional excipients for tablet cores on the quality of applied coatings," by Martin Wewers under the direction of Dr. Jan Henrik Finke at the Technical University of Braunschweig, in Germany. The study was conducted at the university's Institute for Particle Technology (iPAT) and at JRS Pharma, in Rosenberg, Germany.
 
Aqueous film coatings can enhance the appearance, stability, swallowability, and brand identity of pharmaceutical tablets. Coatings can also be used to mask the taste of a bitter or otherwise unpleasant active pharmaceutical ingredient or control its release. The properties of the tablet being coated, including tensile strength, surface roughness, and hydrophobicity can greatly influence coating quality and performance.
 
This article describes a study conducted to investigate the influence of different commonly used lubricants and disintegrants on tablet surface roughness and film coating adhesion. In addition, a commercially available coprocessed excipient for direct compression (Prosolv Easytab) containing silicified microcrystalline cellulose (SMCC), lubricant, and disintegrant was part of the study. The study investigated the influence of two lubricants, magnesium stearate (MgSt) and sodium stearyl fumarate (SSF), and three disintegrants, croscarmellose sodium (CCS), crospovidone (PVPP) and sodium starch glycolate (SSG). The researchers prepared tablets of pure microcrystalline cellulose (MCC), five physical mixtures containing MCC and either disintegrant or lubricant, and the coprocessed excipient. The tensile strength and surface roughness of the tablets as well as the film coating adhesion of aqueous HPMC coatings on these tablets were studied.
 
To learn more about this topic, you can read the article "Formulation effects on tablet surface properties and film coating adhesion." You can also find articles under "Excipients" and "Formulation" in Tablets & Capsules' Article Archive.
 
 
USP

Gelita
 
Industry news
 
 
 
 
 
 
 
 
Natoli

tc
 
Supplier news
 
 
 
 
 
To find more information about suppliers at the Tablets & Capsules website, click here.
 
 
Events and continuing education
 
 
 
 
 
 
 
 
 
 
 
 
 
To find more events and continuing education opportunities at the Tablets & Capsules website, click here.
 
January 13, 2020
 
Facebook spacer Twitter spacer Twitter
 
 
 
Supplier Resources
click below for more info
 
Ackley
 
Camfil
 
CapsCanada
 
Gelita
 
MFG Tray
 
Natoli
 
USP
 
Vac-U-Max
 
Wilson
 
Supplier Directory
 
Anti-Counterfeiting
Ackley Machine

Capsule Filling Equipment
Natoli Engineering
Vac-U-Max

Contract Formulation/
Manufacturing & Packaging

CapsCanada

Conveying/Mechanical
VAC-U-MAX

Dedusters
Natoli Engineering

Dust Collectors
Camfil APC

Empty Capsules
CapsCanada

Excipients
CapsCanada
USP

Feeders
Ackley Machine

Inspection Equipment
Ackley Machine
Natoli Engineering

Metal Detectors/X-Ray Detectors
Natoli Engineering

Packaging Equipment
Ackley Machine
VAC-U-MAX

Pneumatic Conveying
VAC-U-MAX

Services
Ackley Machine
CapsCanada
Natoli Engineering

Softgels
Ackley Machine
MFG Tray Company

Storage/Bulk Handling
MFG Tray Company
VAC-U-MAX

Tablet & Capsule Printers
Ackley Machine
CapsCanada

Tablet Presses
Natoli Engineering

Testing
Natoli Engineering

Tooling
Natoli Engineering
Wilson Tool

Vacuum Cleaners
VAC-U-MAX

Validation
USP

Weighing Equipment
VAC-U-MAX
 
T&C Solid Dosage Sourcebook
 
sourcebook

Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Kyle Myers
T&C Solid Dose Digest
Circulation
kmyers@cscpub.com
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
Copyright 2020, CSC Publishing Inc. All rights reserved.
Tablets & Capsules Insight Newsletter