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Tablets & Capsules SDD

imageIn this issue of T&C Solid Dose Digest:

 
 
 
 
 
 
 
camfilapc

jrs pharma
 
Ask an Expert
 
Combustible dust
 
Q: How do we know if our dust is combustible, and what measures do we need to take to comply with regulations and protect our employees?
 
 
imageAlmost all processes in solid dose manufacturing—such as crushing, screening, sieving, and weighing—create dust, and many of these dusts are combustible. For example, formulators commonly use methylcellulose in tablets as a binder, coating agent, and disintegrant as well as to achieve sustained release of active pharmaceutical ingredients (APIs) [1]. The Occupational Safety and Health Administration (OSHA) identifies methylcellulose as a material that creates a risk of a combustible dust explosion [2].
 
 
 
gelita

mfgtray
 
More Questions and Answers
 
Tip clearance
 
Q: What is tip clearance, and how does it affect tablet production?
 
 
imageFor tablet press tooling, tip clearance is the difference in size between the punch tip and the die bore, which allows the punch to move freely within the die bore during operation. Tip clearance can affect tablet production in a number of ways, including product yield, tablet output, and quality. Operating a tablet press using incorrect tip clearances can cause the tooling to bind.
 
 
 
wilson

jost
 
In Tablets & Capsules magazine
 
The FDA's increasing oversight of E&L testing in pharma
 
 
Extractable and leachable (E&L) testing determines whether unwanted and potentially harmful compounds are pulled out of a product's packaging, delivery system, or manufacturing surface under certain conditions (extractables) or passively migrate into a product over time (leachables). As part of the US FDA guidelines, all drug products in development must be submitted to the FDA for approval, which includes a review of E&L testing.
 
To learn more about this topic, you can read the article "Back Page: The FDA's increasing oversight of E&L testing in pharma.." You can also find articles under "Validation and regulatory compliance" in Tablets & Capsules' Article Archive.
 
 
natoli

nilfisk
 
Industry news
 
 
 
 
vacumax

recro
 
Supplier news
 
 
 
 
To find more information about suppliers at the Tablets & Capsules website, click here.
 
 
kikusui

tc
 
Events and continuing education
 
 
 
 
 
 
 
To find more events and continuing education opportunities at the Tablets & Capsules website, click here.
 
December 9, 2019
 
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Supplier Resources
click below for more info
 
gelita
 
camfil
 
mfgtray
 
kikusui
 
vacumax
 
recro
 
nilfisk
 
natoli
 
jrs pharma
 
jost
 
wilson
 
Supplier Directory
 
Capsule Filling Equipment
Vac-U-Max

Coating
(Equipment & Coatings)

JRS Pharma

Contract Formulation/
Manufacturing & Packaging

Recro Gainesville

Conveying/Mechanical
VAC-U-MAX

Dedusters
Natoli Engineering

Dust Collectors/Filters
Camfil APC
Nilfisk Industrial Vacuums
VAC-U-MAX

Excipients
Gelita
Jost Chemical
JRS Pharma

Feeders
VAC-U-MAX

Inspection Equipment
Natoli Engineering

Lifters
VAC-U-MAX

Metal Detectors/X-Ray Detectors
Natoli Engineering

Mixers & Blenders
VAC-U-MAX

Pneumatic Conveying
Nilfisk Industrial Vacuums
VAC-U-MAX

Services
Natoli Engineering
VAC-U-MAX
Wilson Tool

Softgels
MFG Tray Company

Storage/Bulk Handling
MFG Tray Company
VAC-U-MAX

Tablet Presses
Kikusui USA Inc.
Natoli Engineering

Testing Equipment
Natoli Engineering

Tooling
Natoli Engineering
Wilson Tool

Vacuum Cleaners
Nilfisk Industrial Vacuums
VAC-U-MAX

Weighing Equipment
VAC-U-MAX
 
T&C Solid Dosage Sourcebook
 
sourcebook

Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Kyle Myers
T&C Solid Dose Digest
Circulation
kmyers@cscpub.com
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
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