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Tablets & Capsules SDD
imageIn this issue of T&C Solid Dose Digest:
 
 
 
 
 
 
 
mfgtray

wilson
 
Ask an Expert
 
Dust collectors for modular processing
 
Q: Can a compact, cartridge dust collector provide effective dust collection for modular cleanrooms and processing suites?
 
A: David Steil, Camfil Air Pollution Control, says:
 
imageSelf-contained, modular, autonomous cleanrooms and processing suites are revolutionizing pharmaceutical solid-dose processes. These systems are readily deployable, mobile, and scalable and are ideal for multiproduct sites, rigorous containment needs, and on-demand scaling of production and laboratory space. In many cases, you can repurpose these suites to manufacture a different product quickly and easily, which is an important benefit.
 
 
 
jost

natoli
 
More Questions and Answers
 
Tablet hardness, capsule shell strength
 
Q: How important is it to assess tablet hardness and capsule shell strength for a newly formulated drug product?
 
 
imageOral administration is a widely used route of drug delivery around the world, and tablets and capsules are a convenient way to administer formulations to patients.

Tablets are the most widely used dosage form, and tablet hardness is a critical attribute for successful active pharmaceutical ingredient (API) delivery. A poorly compacted tablet can accelerate disintegration due to weak bonding and cause premature API release, while an extremely hard tablet can slow a tablet's dissolution due to excessive bonding between the API(s) and excipients and decrease API bioavailability.
 
 
 
nilfisk

vacumax
 
In Tablets & Capsules magazine
 
Deconstructing silos with an integrated outsourcing model
 
Peter Scholes, Quotient Sciences
 
Functional outsourcing is widely used in the pharmaceutical industry to manage R&D costs and address capacity constraints. However, the rise in outsourcing over the last 10 years has fundamentally changed the industry's structure. These changes have created a siloed mentality, in which various vendors each handle an individual piece of the process—from discovery to formulation development to manufacturing. This has magnified existing time and cost inefficiencies in the drug development process and increased the time it takes for drug molecules to reach the proof-of-concept (POC) stage and beyond.
 
With time and money at a premium, drug companies need to bring new molecules to market as quickly as possible. One approach is to focus on smarter R&D by aligning the activities of the contract development and manufacturing organization (CDMO) and the contract research organization (CRO) into one highly integrated model. A single outsourcing partner coordinates and adapts the drug product manufacturing requirements ("make") with the specific needs of the clinical development plan ("test"). Unlike outsourcing multiple development activities to numerous firms, this integrated CDMO/CRO approach improves efficiencies to achieve milestones under a compressed timeline.
 
To learn more about this topic, you can read the article "Back Page: Deconstructing silos with an integrated outsourcing model." You can also find articles under "Outsourcing" in Tablets & Capsules' Article Archive.
 
 
recro

kikusui
 
Industry news
 
 
 
 
 
 
 
camfilapc

jrs pharma
 
Supplier news
 
 
 
 
 
 
 
 
To find more information about equipment suppliers at the Tablets & Capsules website, click here.
 
 
gelita

tc
 
Events and continuing education
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
To find more events and continuing education opportunities at the Tablets & Capsules website, click here.
 
August 12, 2019
 
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Supplier Resources
click below for more info
 
kikusui
 
vacumax
 
recro
 
nilfisk
 
natoli
 
jrs pharma
 
jost
 
wilson
 
gelita
 
camfil
 
mfgtray
 
Supplier Directory
 
Capsule Filling Equipment
Vac-U-Max

Coating
(Equipment & Coatings)

JRS Pharma

Contract Formulation/
Manufacturing & Packaging

Recro Gainesville

Conveying/Mechanical
VAC-U-MAX

Dedusters
Natoli Engineering

Dust Collectors/Filters
Camfil APC
Nilfisk Industrial Vacuums
VAC-U-MAX

Excipients
Gelita
Jost Chemical
JRS Pharma

Feeders
VAC-U-MAX

Inspection Equipment
Natoli Engineering

Lifters
VAC-U-MAX

Metal Detectors/X-Ray Detectors
Natoli Engineering

Mixers & Blenders
VAC-U-MAX

Pneumatic Conveying
Nilfisk Industrial Vacuums
VAC-U-MAX

Services
Natoli Engineering
VAC-U-MAX
Wilson Tool

Softgels
MFG Tray Company

Storage/Bulk Handling
MFG Tray Company
VAC-U-MAX

Tablet Presses
Kikusui USA Inc.
Natoli Engineering

Testing Equipment
Natoli Engineering

Tooling
Natoli Engineering
Wilson Tool

Vacuum Cleaners
Nilfisk Industrial Vacuums
VAC-U-MAX

Weighing Equipment
VAC-U-MAX
 
T&C Solid Dosage Sourcebook
 
sourcebook

Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Kyle Myers
T&C Solid Dose Digest
Circulation
kmyers@cscpub.com
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
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