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Tablets & Capsules SDD
imageIn this issue of T&C Solid Dose Digest:
 
 
 
 
 
 
 
 
camfilapc

gelita
 
Ask an Expert
 
3D manufacturing for tablets and capsules
 
Q: What are the applications, limitations, and considerations for use of 3D printing of tablets and capsules?
 
 
Patients are already benefiting from 3D-printed medical products through access to personalized devices and groundbreaking medicines. Suppliers are developing custom-fitted medical devices ranging from hearing aids and dental aligners to prosthetic limbs tailor-made for patients' specific needs. Established and new players in the pharmaceutical industry are investing in research into 3D-printing applications, such as pharmaceutical tablets. According to a report by IDTechEx, the market for 3D printing in the medical industry will exceed $8.1 billion by 2029 [1].
 
 
 
wilson

jost
 
Tooling: Facts versus Fiction
 
Tablet press parts and tablet quality
 
Q: Which tablet press parts have the greatest effect on overall tablet quality?
 
imageA: Doug Kirsch, Natoli Engineering, says:
 
Troubleshooting tableting defects can be difficult. Determining whether the fault lies in the tooling, the formulation being compressed, the press itself, or a combination of these can take a significant amount of time.
 
 
 
natoli

nilfisk
 
In Tablets & Capsules magazine
 
Tableting performance using lactose-based excipients
 
Federica Giatti and Caterina Funaro, IMA Active and
Vera Fichtner and Franz Penz, Meggle
 
This article describes a study conducted to measure the tableting performance of vitamin B2 and C mini-tablets using lactose-based excipients.
 
Mini-tablet use continues to grow as an accepted option for small-volume, high-value products, especially for specific patient populations. Mini-tablet applications, as either single- or multi-tablet units, allow for fixed-dose combinations and dose titrations [1]. Because of their small size (typically less than 3.0 millimeters in diameter), mini-tablets also offer an approach for populations that have difficulty swallowing traditional tablets and capsules, such as pediatric and geriatric patients or patients suffering from dysphagia.
 
This article describes a study that was designed to demonstrate an experimental design, equipment feasibility, lactose-based excipient performance, and critical material attributes within a typical mini-tablet manufacturing operation. Example formulations were chosen to investigate compaction and release performance as well as the impact of particle size using two different active pharmaceutical ingredients (APIs) and three functional excipients. Each formulation consisted of a powder blend comprising 10 percent API, 89 percent excipient, and 1 percent lubricant.
 
To learn more about this topic, you can read the article "Eye on excipients: Tableting performance using lactose-based excipients." You can also find articles listed under "Excipients" in Tablets & Capsules' Article Archive.
 
 
vacumax

recro
 
46th annual Controlled Release Society (CRS) annual meeting & exposition
 
The 46th annual CRS meeting and exposition will take place on July 21-24 at the Palacio de Congresos de València, in Valencia, Spain. More than 1,200 industry and academic professionals focused on drug delivery, pharmaceutical science, consumer and diversified products, preclinical science, and animal health are expected to attend this year's show. It will include half- and full-day pre-meeting workshops; networking groups and scientific sessions; a show floor, providing interaction with exhibitors and poster presenters; a plenary session with Ralph Weissleder, Harvard Medical School, on new approaches in imaging and sensing of drug action; and a closing session and awards ceremony.
 
Register today for the upcoming 46th annual CRS meeting and exposition.
 
 
kikusui

tc
 
Industry news
 
 
 
Supplier news
 
 
 
 
 
 
 
To find more information about equipment suppliers at the Tablets & Capsules website, click here.
 
Events and continuing education
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
To find more events and continuing education opportunities at the Tablets & Capsules website, click here.
 
June 24, 2019
 
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Supplier Resources
click below for more info
 
jost
 
wilson
 
gelita
 
camfil
 
kikusui
 
vacumax
 
recro
 
nilfisk
 
natoli
 
Supplier Directory
 
Capsule Filling Equipment
Vac-U-Max

Contract Formulation/
Manufacturing & Packaging

Recro Gainesville

Conveying/Mechanical
VAC-U-MAX

Dedusters
Natoli Engineering

Dust Collectors/Filters
Camfil APC
Nilfisk Industrial Vacuums
VAC-U-MAX

Excipients
Gelita
Jost Chemical

Feeders
VAC-U-MAX

Inspection Equipment
Natoli Engineering

Lifters
VAC-U-MAX

Metal Detectors/X-Ray Detectors
Natoli Engineering

Mixers & Blenders
VAC-U-MAX

Pneumatic Conveying
Nilfisk Industrial Vacuums
VAC-U-MAX

Services
Natoli Engineering
VAC-U-MAX
Wilson Tool

Storage/Bulk Handling
VAC-U-MAX

Tablet Presses
Kikusui USA Inc.
Natoli Engineering

Testing Equipment
Natoli Engineering

Tooling
Natoli Engineering
Wilson Tool

Vacuum Cleaners
Nilfisk Industrial Vacuums
VAC-U-MAX

Weighing Equipment
VAC-U-MAX
 
T&C Solid Dosage Sourcebook
 
sourcebook

Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Kyle Myers
T&C Solid Dose Digest
Circulation
kmyers@cscpub.com
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
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