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Tablets & Capsules SDD
imageIn this issue of T&C Solid Dose Digest:
 
 
 
 
 
 
 
jost

natoli
 
Ask an Expert
 
Roller compaction granulation
 
Q: What are the advantages of roller compaction granulation compared to traditional wet granulation?
 
 
imageGranulation is a process in which primary powder particles adhere to each other, resulting in larger, homogeneous, multiparticle entities called granules. In wet granulation, manufacturers add a liquid binder to the powder blend and then dry the mixture, causing the primary particles to bind together and form granules. However, the use of liquids and high drying temperatures makes wet granulation unsuitable as a manufacturing method for some moisture- or heat-sensitive blends or blends with low melting points.
 
 
 
nilfisk

vacumax
 
Tooling: Facts versus Fiction
 
Proper cleaning for tooling
 
Q: What is the best way to clean tablet compression tooling?
 
A: Natoli technical team, Natoli
 
Punches and dies are a big investment that you should protect by careful handling and thorough cleaning. Dirty tooling is the chief cause of tablet-press failure, and clean tooling is critical to producing consistent, high-quality tablets. Clean punches and dies are essential to maintaining the integrity and efficiency of your tooling. Excessively worn or improperly maintained tools can create downstream production difficulties and a perception of poor quality for the consumer.
 
 
 
recro

kikusui
 
Feature
 
Blister packaging: Benefits, trends, and innovations
 
Tom Egan, PMMI, says:
 
This article discusses the safety, product stability, and consumer convenience benefits of blister packaging for solid oral dosage pharmaceutical products.
 
Invented in the early 1960s and heralded for its convenience and security, the blister pack was designed to improve medication compliance. Indeed, for the birth-control pill, which became the first pharmaceutical product to leverage the blister-pack format, patient compliance was critical. For the pill to be effective in preventing pregnancy, Schering (now Bayer) needed a packaging format that made it easy for consumers to administer doses regularly over a set period of time. The development of polyvinyl chloride (PVC) and copolymers with good thermoforming capabilities, along with tempered aluminum foil as a lidding material, helped make commercialization of the blister pack possible [1].
 
More than 50 years later, the blister pack is becoming increasingly popular as a packaging format perfectly suited for today's security-minded consumers and regulators. Blister packaging not only works well with track-and-trace and serialization protocols but also helps with anti-counterfeiting efforts. And the blister pack remains the best packaging format for improving patient compliance, whether for an over-the-counter (OTC) pain reliever or a groundbreaking clinical-trial medication.
 
For more information on this topic, you can read the article "Blister packaging: Benefits, trends, and innovations," by Tom Egan, PMMI. You can also find articles listed under "Packaging" in Tablets & Capsules' Article Archive.
 
 
camfilapc

gelita
 
Industry news
 
 
 
 
 
 
 
wilson

tc
 
Supplier news
 
 
 
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Events and continuing education
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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March 25, 2019
 
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Supplier Resources
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Supplier Directory
 
Capsule Filling Equipment
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Contract Formulation/
Manufacturing & Packaging

Recro Gainesville

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Dedusters
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Dust Collectors/Filters
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Natoli Engineering
Wilson Tool

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Nilfisk Industrial Vacuums
VAC-U-MAX

Weighing Equipment
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T&C Solid Dosage Sourcebook
 
sourcebook

Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Judie Hadley
T&C Solid Dose Digest
Circulation
jhadley@cscpub.com
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
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