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Tablets & Capsules SDD
imageIn this issue of T&C Solid Dose Digest:
 
 
 
 
 
 
 
recro

nilfisk
 
In Tablets & Capsules magazine
 
Optimizing your tablet press tooling
 
Mike Beyl, Wilson Tool International says:
 
Optimizing your tablet press tooling can help increase production and tool life while reducing costs and downtime. This article discusses several aspects of tooling optimization and explains how to start small by optimizing the tooling for one product at a time.
 
Tablets come in many shapes and sizes, and tablet formulations have a range of physical characteristics and tableting properties, such as abrasiveness, corrosiveness, lubricity, and compressibility. With this in mind, it makes sense that a one-size-fits-all approach to tablet press tooling is unlikely to provide the best results for companies that manufacture a range of pharmaceutical or nutraceutical tablets. By optimizing your tooling to suit the product being manufactured, you can minimize tableting problems such as picking, sticking, fracture, and excessive wear.
 
The main factors to consider when optimizing your tooling are the tablet and tool design; the steel used to make the tooling; and the coating, if any, applied to the tooling. Once you have a good understanding of how these factors influence tableting performance, you can evaluate your existing tooling and your tableting processes to identify where optimization may have the most impact.
 
For more information on this topic, you can read the article "Optimizing your tablet press tooling," by Mike Beyl, Wilson Tool International. You can also find articles under "Tablets and tabletting" and "Tooling" in Tablets & Capsules' Article Archive.
 
 
kraemer

natoli
 
Ask an Expert
 
OCR formulation and processing
 
Q: What planning should my company do to ensure success for oral controlled-release drug products?
 
 
imageIn oral controlled-release (OCR) product development, decisions you make at the outset determine your success. Selecting the final dosage form, developing your approach to formulation and processing, and avoiding common roadblocks are key. While a surprisingly wide variety of OCR formulations are possible, faulty planning for development and manufacturing can cost you time and money and can potentially end the whole project.
 
 
 
vacumax

kikusui
 
More Questions and Answers
 
Continuous manufacturing
 
Q: How can we avoid increasing our facility's size when adding high-speed, high-throughput continuous-manufacturing equipment?
 
A: Boris Pazovskiy, Nilfisk, says:
 
imageAlthough the pharmaceutical industry has been discussing continuous manufacturing for some time, recently companies have been moving more quickly to implement its processes.
 
In part, this is because of the increased availability of high-speed, high-throughput processing equipment, which has a very high demand for material. For example, some new multilayered tablet presses and encapsulation machines can process 3,000 to 4,000 kilograms of material per hour. Imagine an operator scooping material into a machine in that scenario. Even two operators steadily scooping 1 kilogram per minute could supply only a tenth of the material the machines can handle.
 
 
jrs

jost
 
Industry news
 
 
 
 
 
 
 
 
alfacaps

camfilapc
 
Supplier news
 
 
 
 
 
 
 
 
 
 
To find more information about equipment suppliers at the Tablets & Capsules website, click here.
 
November 12, 2018
 
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Supplier Directory
 
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Alfacaps

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Recro Gainesville

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Natoli Engineering

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Camfil APC
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Kraemer
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Kikusui USA Inc.
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Natoli Engineering

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Natoli Engineering

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Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Judie Hadley
T&C Solid Dose Digest
Circulation
jhadley@cscpub.comn
 
Kurt Beckman
T&C Solid Dose Digest
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Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
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