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Tablets & Capsules SDD
imageIn this issue of T&C Solid Dose Digest:
 
 
 
 
 
 
 
camfilapc

recro
 
Ask an Expert
 
Continuous vacuum conveying
 
Q: Why should my company move to continuous vacuum conveying?
 
A: Doan Pendleton, Vac-U-Max, says:
 
imageBetween 2004 and 2015, the number of newly-approved pharmaceuticals and nutraceuticals grew rapidly, but the number of drug recalls also grew by over 1,200 percent [1].
 
Although pharmaceutical manufacturers have made technological advancements in formulating drugs, their underlying manufacturing processes are still largely the same, with most companies continuing to rely on batch processing. While reliable, batch processing is slow, and the amount of time and the number of process steps required between batches increase the risk of contamination or human error.
 
 
 
nilfisk

kraemer
 
More Questions and Answers
 
Tablet compression training
 
Q: I need tablet compression training. How do I decide which course is right for me?
 
A: Jonathan Gaik, Natoli Engineering, says:
 
imageTablet compression is complicated, and most who work in the industry learn on the job, but a growing number of options are available to supplement on-the-job training. These options provide press operators, R&D scientists, and maintenance technicians with more formal instruction on topics such as formulation development, process development and scale-up, press maintenance, and troubleshooting manufacturing issues.
 
You can learn more about tablet compression by watching videos or webinars, attending lectures or demonstrations, or participating in hands-on or company-specific workshops. In this article, I discuss some pros and cons for each training type to help you find the right course.
 
 
natoli

vacumax
 
Feature
 
Formulating tablets containing moisture-sensitive actives
 
Pankaj Rege, Colorcon says:
 
R&D groups are often under pressure to shorten a product's time-to-market and are thus demanding more functionality and performance from excipients and coatings.
 
This quest for performance is especially important when the drug product includes one or more moisture-sensitive active pharmaceutical ingredients (APIs) because potential problems associated with these APIs include poor flow properties, variable dissolution rates, and chemical/physical instability (hydrolysis, color change, etc.). As a result, formulators are seeking cost-effective excipients for the tablet core that minimize moisture sensitivity and film coatings that provide a moisture barrier. In fact, the stability of moisture-sensitive drug products depends on how well R&D groups address key formulation and processing variables, including core excipients, film coatings, and process parameters, as well as packaging materials.
 
For more information on this topic, you can read the article "Back Page: Formulating tablets containing moisture-sensitive actives," by Pankaj Rege, Colorcon. You can also find articles listed under "Excipients," "Formulation," and "Tablet coating" in Tablets & Capsules' Article Archive.
 
 
kikusui

jrs
 
Industry news
 
 
 
 
 
 
jost

alfacaps
 
Supplier news
 
 
 
 
To find more information about equipment suppliers at the Tablets & Capsules website, click here.
 
October 22, 2018
 
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Supplier Resources
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camfil
 
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jrs
 
recro
 
Supplier Directory
 
Capsule Filling Equipment
Alfacaps

Coating(s) & Equipment
JRS Pharma

Contract Formulation/ Manufacturing & Packaging
Recro Gainesville

Conveying/Mechanical
VAC-U-MAX

Dedusters
Kraemer
Natoli Engineering

Dust Collectors/Filters
Camfil APC
Nilfisk Industrial Vacuums
VAC-U-MAX

Empty Capsules
Alfacaps

Excipients
Jost Chemical
JRS Pharma

Feeders
VAC-U-MAX

Inspection Equipment
Kraemer
Natoli Engineering

Metal Detectors/X-Ray Detectors
Natoli Engineering

Pneumatic Conveying
Nilfisk Industrial Vacuums
VAC-U-MAX

Services
Natoli Engineering

Storage/Bulk Handling
VAC-U-MAX

Tablet Presses
Kikusui USA Inc.
Natoli Engineering

Testing Equipment
Natoli Engineering

Tooling
Natoli Engineering

Vacuum Cleaners
Nilfisk Industrial Vacuums

Weighing Equipment
VAC-U-MAX
 
T&C Solid Dosage Sourcebook
 
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Events and continuing education
 
 
 
 
 
 
 
 
 
 
 
 
Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Judie Hadley
T&C Solid Dose Digest
Circulation
jhadley@cscpub.comn
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Nate Todd
Tablets & Capsules
Editor
ntodd@cscpub.com
 
 
 
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