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Tablets & Capsules SDD
imageIn this issue of T&C Solid Dose Digest:
 
 
camfilapc

nilfisk
 
Ask An Expert
 
Taste masking
 
Q: What are some strategies for masking the taste of a bitter API?
 
 
The development and optimization of taste-masking formulations, especially for pediatric drug products, continues to be an important aspect of solid oral dosage formulation. This article examines several techniques to overcome the bitter or unpleasant taste of some active pharmaceutical ingredients.
 
 
Do you have a question for our experts? Send your questions to pwright@cscpub.com, and we'll have an expert answer them.
 
natoli

vacumax
 
Tooling: Facts versus Fiction
 
Reducing costs
 
Q: How can I reduce costs without losing quality or decreasing efficiency?
 
imageA: Stephen Natoli, Natoli Engineering says:
 
Reducing costs while maintaining or increasing output and efficiency has become a common mandate across the tableting industry. Although this directive can seem daunting, one of the easiest and most impactful ways to reduce costs is to create and follow proper maintenance procedures for tablet presses and tablet compression tooling. Not only can you reduce costs, you can increase efficiency and production yields while maintaining tablet quality. Maintenance procedures should cover proper cleaning and handling, setting up an inspection process, maintaining your tooling and tablet press, and considering various tooling options.
 
 
kikusui

jrs
 
More Questions and Answers
 
Mini-tablets
 
Q: What are the advantages of mini-tablets for pediatric and geriatric patients?
 
 
imageDeveloping a drug product for pediatric or geriatric patients is often challenging because a single product may not be viable for all patients within each group. In both groups, swallowing abilities and taste preferences make choosing dosing regimens for traditional solid dosage forms more challenging.
 
 
 
jost

alfacaps
 
In Tablets & Capsules magazine
 
Basic batch coater operating parameters and setup
 
Nicholas S. Slater, Freund-Vector
 
This article discusses the basic operating parameters and setup for a perforated pan film coater.
 
Film coating is a widely used process in tablet manufacturing. Applying a clear or colored aqueous or solvent-based coating can improve a pharmaceutical tablet's appearance, taste, and/or swallowability; make it stronger or easier to handle; or modify its API-release properties. Tablet coating isn't an overly complex process, but proper coater setup and operating parameters ensure that your tablets are coated evenly and adequately without defects.
 
While the coating formulation and the equipment design also impact coating quality, in this article we will focus on the qualitative relationships between key parameters when using a fully perforated pan film coater. Understanding these parameters and their effects on the coating process will help you perform basic setup and problem solving with your coating system. Note that this article isn't a comprehensive guide to coater setup and operation; it's just a beginning step toward continuous improvement and training for coating equipment operators.
 
To learn more about this topic, you can read the article "Basic batch coater operating parameters and setup." You can also find articles under "Tablet coating" in Tablets & Capsules' Article Archive.
 
 
jost
 
Feature
 
Put it in a capsule
 
Gabriel Eilemberg, CapsCanada
 
Oftentimes, when deciding whether to formulate a drug product or dietary supplement in capsule or tablet form, manufacturers and brand owners fail to consider all the variables, the big picture. Instead they focus on single factors, such as production speed, thinking high speed will lower costs and raise profits.
 
That's not always the case. There are other important considerations that, when taken into account, make capsules a much more attractive choice—from a financial, operational, and marketing perspective.
 
For more information on this topic, you can read the article "Back Page: Put it in a capsule," by Gabriel Eilemberg, CapsCanada. You can also find articles listed under "Capsules and capsule filling" in Tablets & Capsules' Article Archive.
 
 
jost
 
PBE Powder Show™
 
Register today for the upcoming 2018 PBE Southeast Powder Show™ & Conference
 
imageRegister by August 31 to receive discount pricing on the 2018 PBE Southeast Powder Show's™ conference program. It is the only dedicated powder and bulk solids show for North America in 2018 and will be held September 25-27 at the Charlotte Convention Center in Charlotte, NC. To learn more and to register, click here.
 
 
Industry news
 
 
 
May 21, 2018
 
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Supplier Resources
click below for more info
 
jrs
 
kikusui
 
vacumax
 
natoli
 
nilfisk
 
camfil
 
jrs
 
jost
 
Supplier Directory
 
Capsule Filling Equipment
Alfacaps

Coating(s) & Equipment
JRS Pharma

Conveying/Mechanical
VAC-U-MAX

Dedusters
Natoli Engineering

Dust Collectors/Filters
Camfil APC
Nilfisk Industrial Vacuums
VAC-U-MAX

Empty Capsules
Alfacaps

Excipients
Jost Chemical
JRS Pharma

Feeders
VAC-U-MAX

Inspection Equipment
Natoli Engineering

Metal Detectors/X-Ray Detectors
Natoli Engineering

Pneumatic Conveying
Nilfisk Industrial Vacuums
VAC-U-MAX

Services
Natoli Engineering

Storage/Bulk Handling
VAC-U-MAX

Tablet Presses
Kikusui USA Inc.
Natoli Engineering

Testing Equipment
Natoli Engineering

Tooling
Natoli Engineering

Vacuum Cleaners
Nilfisk Industrial Vacuums

Weighing Equipment
VAC-U-MAX
 
T&C Solid Dosage Sourcebook
 
sourcebook
Supplier news
 
 
 
To find more information about equipment suppliers at the Tablets & Capsules website, click here.
 
Events & continuing education
 
 
 
 
 
 
 
 
 
 
 
 
To find more events and continuing education opportunities at the Tablets & Capsules website, click here.
 
Send your feedback or questions to Peggy Wright at pwright@cscpub.com.
Peggy Wright
T&C Solid Dose Digest
Editor
pwright@cscpub.com
 
Kurt Beckman
T&C Solid Dose Digest
Designer
kbeckman@cscpub.com
 
Judie Hadley
T&C Solid Dose Digest
Circulation
jhadley@cscpub.com
 
 
 
 
Copyright 2018, CSC Publishing Inc. All rights reserved.
Tablets & Capsules Insight Newsletter