Tablets & Capsules magazine with technical articles and North American manufacturer links

Wednesday, March 10, 2010

Current Issue

Tablets & Capsules is the only technical publication devoted exclusively to readers in the tablet and capsule processing industries.

Complete table of contents

				This Month's Focus: Outsourcing
		Containment of high-potency drug products: Outsourcing and other challenges (Free) In this article, outsourcing providers, containment equipment suppliers, and consultants discuss containment challenges, including outsourcing, scale-up, and product and operator safety. General Features Over-encapsulation: Techniques and challenges of blinding clinical trial materials Over-encapsulation is the most widely used method of blinding supplies in clinical studies, which are larger, more complex, and spread through more countries than ever before. This article reviews techniques for successful over-encapsulation and suggests solutions to common problems. Separation anxiety: Addressing variation in content uniformity data in compression processes Pharmaceutical scientists are responsible for developing formulas and designing processes that ensure the content uniformity of tablets and capsules. Unfortunately, a number of scientists who formulate products or select and/or design processing equipment lack in-depth understanding of powder blending and segregation. As a result, processes may be developed that are not capable of providing the required content uniformity of the dosage units. This article focuses on identifying and addressing variation in content uniformity. Spotlight on Nutraceuticals: Reduce visual inspection of capsules by building quality in This article discusses the limitations of visual capsule inspection and offers basic guidance on how to build quality into your capsule filling process. Eye on Excipients: Third-party auditing As the pharmaceutical industry fights the spread of adulterated and counterfeit products, the FDA and others are relying more and more on supplier audits. This edition of the column addresses the advantages and potential problems of establishing a system of third-party auditing.