This Month’s Focus: Excipients & Formulation
Effervescent technology for today’s pharmaceuticals and dietary supplements
Effervescence is an underused formulation approach that offers functional and consumer advantages over conventional products. While the basic chemistry and process technology isn’t new, their complexity requires special formulation and manufacturing techniques. Here are the important factors to consider.
Properties of mucoadhesive polymers and their use in tablets and other dosage forms
This article describes how several specialty polymers are used to formulate swallowable (peroral), buccal, and sublingual tablets, as well as topicals, suspensions, solutions, and mucoadhesive products.
Improving the bioavailability APIs for delivery in oral solid dosage forms
Good aqueous solubility is a key consideration to obtaining a bioavailable product. This article summarizes some of the techniques used to improve solubility and/or absorption. They include modifying the chemical structure, changing the physical form, reducing the particle size, and using fit-for-purpose excipients.
Spotlight on Nutraceuticals: How to boost ingredient quality and promote its value to customers
When it comes to nutraceutical ingredients, quality is one of the most scrutinized characteristics and it’s often referenced in a product’s marketing materials. While inspection can help you verify quality, suppliers must take many other steps to build quality into the product. This article explains one supplier’s approach and how companies can use quality to market their products.
Tips for taking samples from blended batches
You take samples during batch blending to determine whether the batch is blended properly to meet your customer’s specifications or the requirements of a downstream process. This article discusses sample size, frequency and methods.
Back Page: Options for conducting elemental impurities testing
You must test at concentrations that depend on the permissible daily exposure (PDE) based on the route of administration and daily dose.
The evolution of tablet presses: Better operation, changeover, and maintenance
Tablet press paddle feeders: How they affect powder flow
Liquid capsule filling
January: Capsule Filling
June: Solid Dosage Sourcebook
July: Excipients & Formulation
October: Quality, Validation & Regulatory Compliance
November: Annual Buyer’s Guide
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2. Dissolution Testing
2. Multi-layer Tabletting
2. Powder Transfer & Containment
2. Mixers & Blenders
2. Tablet & Capsule Identification