This Month’s Focus: Capsule Filling
Resolving weight variation on tamping-style capsule fillers
Weight variation in filled two-piece capsules is a common occurrence. This article tells you why the weight of your filled capsules can vary and how to fix the problem.
How to assess and prevent brittleness of hard gelatin capsules
When pharmaceutical manufacturers discover capsules that perform poorly because of brittleness, they often attribute the problem to manufacturing processes or storage conditions. But many other factors can lead to brittle capsules.
Las Vegas manufacturer finds capsule fillers a safe bet
At DrVita, Bosch equipment fills more than 90 percent of its capsule products.
Back Page: HPMC capsules and hygroscopic fills: Some clarification
The literature includes many references to HPMC capsules being useful when filling hygroscopic formulations. Make sure you to understand that usefulness correctly.
Spotlight on Nutraceuticals: Rough going? Tips for fighting abrasive wear of punches and dies
Compressing abrasive nutraceuticals can wear tooling prematurely and cause other problems. This article discusses using wear-resistant tooling steel, anti-abrasive coatings, and good tablet design to extend the service life of your punches and dies.
Elusive endpoint? Physical standardization offers an alternative
Traditional high-shear granulation is not well understood, and it’s difficult to predict when the process is finished. This article describes a method that overcomes the drawbacks of relying only on probes and fixed liquid additions to reach the endpoint.
Amway opts for integrated packaging lines
Company selects one vendor to supply and install two bottling lines and to train the operators.
Eye on Excipients: Novel film coating polymer
The authors summarize the results of a study in which a film coating that includes a novel polymer was applied to tablets at low bed temperatures.
Evolution of capsule polymers
Measuring the porosity of solids
New dust collection standard
January: Capsule Filling
June: Solid Dosage Sourcebook
July: Excipients & Formulation
October: Quality, Validation & Regulatory Compliance
November: Annual Buyer’s Guide
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2. Multi-layer Tabletting
2. Powder Transfer & Containment
2. Mixers & Blenders
2. Tablet & Capsule Identification